IgG Food Explorer
Evaluate Over 250* Food Sensitivities With a Simple At-Home Collection!
The IgG Food Explorer™ by Diagnostic Solutions Laboratory is an Elisa-based multiplex food sensitivity test measuring total IgG antibodies to an overabundance of foods.
IgG Food Explorer evaluates over 250 food antigens using a simple at-home collection. Results help practitioners personalize diet and lifestyle guidance for their patients to reduce and eliminate symptoms related to adverse food reactions.
Documents
Explore our IgG Food Explorer educational resources. Learn about the markers on the test and how they impact overall health so you can better interpret results.
Clinical Information
IgG Food Explorer tests antibody response to over 250* food extracts. Molecular antigens for wheat gliadin and cow's milk are also included for enhanced insight into the sensitivity of those two potentially immunogenic foods.
What are Food Sensitivities?
Food sensitivities are an adverse immune system response to ordinarily harmless foods. These food sensitivities are highly individualized, and symptoms are subtle and often delayed. Adverse reactions can occur from 3 to 72 hours after ingesting the offending food.
Why Test for Food Sensitivities?
Elevated IgG antibodies can promote systemic (whole-body) inflammation, leading to a variety of unwanted symptoms.
IgG Food Explorer tests immunoglobulin (IgG) antibodies to a variety of common foods. This extensive food sensitivity test can help practitioners pinpoint which foods may be driving symptoms and best prioritize and individualize a diet and lifestyle plan for patients.
Usually, eliminating foods that promote an IgG antibody response can reduce stress on the immune system, lower whole-body inflammation, and help heal the gut. An antibody-guided elimination diet is more reliable and preferable than generalized diet plans or exclusion diets based on food journaling and diet history alone.
IgG Food Explorer provides in-depth insight into adverse food reactions and the symptoms they create.
Why Choose the IgG Food Explorer?
Simple, Convenient, and Impactful Insight into Symptoms Caused by Foods
The IgG Food Explorer uses an ELISA-based microarray testing panel that specifically and sensitively quantifies IgG antibodies present within a sample.
Using a simple finger-stick blood collection, the IgG Food Explorer is a convenient collection that offers impactful insight into symptoms caused by foods.
Testing allows practitioners to tie patient symptoms directly back to adverse reactions to foods. Food sensitivities can then be addressed through diet to help resolve symptoms and optimize health.
Patient Information
Are You a Patient? A healthcare practitioner will need to order the test for you. That can be your own doctor, or contact us so we can help you find a practitioner in your area. Ask your practitioner about IgG Food Explorer, and how it can help you achieve better health!
Optimizing Your Health
We know you want to be proactive about your health. IgG Food Explorer can help your doctor evaluate how you function to either optimize your current health or identify health issues that need attention. Our goal is to help you achieve your health goals through research-based testing and treatment protocols tailored to your unique needs.
Understanding Food Sensitivities vs. Food Allergies
Food sensitivities and food allergies are not the same. Different arms of the immune system facilitate both conditions. Food sensitivities are delayed reactions and elicit IgG antibodies, while food allergies are immediate, potentially life-threatening, mast-cell mediated, and often involve IgE antibodies.
It is best practice to measure IgG and IgE antibodies together as they independently create inflammation and play key roles in symptoms driven by food. A food can elicit an IgG sensitivity response, and an IgE antibody response, or both.
By understanding a patient's food sensitivities, practitioners can tailor dietary protocols that can help resolve uncomfortable symptoms.
NOTE: IgG Food Explorer does not test for dietary intolerances (such as lactose intolerance) and does not test for celiac disease-specific antibodies.
Interested in testing for food and environmental allergies in addition to IgG food sensitivities? Learn about IgE Allergy Explorer, a companion immune response profile to the IgG Food Explorer.
REFERENCES
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- Taheri S. Effect of exclusion of frequently consumed dietary triggers in a cohort of children with chronic primary headache. Nutr Health. 2017;23(1):47-50.
- Steelant B, Farré R, Wawrzyniak P, et al. Impaired barrier function in patients with house dust mite-induced allergic rhinitis is accompanied by decreased occludin and zonula occludens-1 expression. J Allergy Clin Immunol. 2016;137(4):1043-1053.e5.
- Sheen YH, Jee HM, Kim DH, et al. Serum zonulin is associated with presence and severity of atopic dermatitis in children, independent of total IgE and eosinophil. Clin Exp Allergy. 2018;48(8):1059-1062.
- Vancamelbeke M, Vermeire S. The intestinal barrier: a fundamental role in health and disease. Expert Rev Gastroenterol Hepatol. 2017 Sep;11(9):821-834. doi: 10.1080/17474124.2017.1343143. Epub 2017 Jun 26. PMID: 28650209; PMCID: PMC6104804.
- Camilleri M. Leaky gut: mechanisms, measurement and clinical implications in humans. Gut 2019;68:1516-1526.
- Mu Q, Kirby J, Reilly CM, Luo XM. Leaky Gut As a Danger Signal for Autoimmune Diseases. Front Immunol. 2017;8:598. Published 2017 May 23. doi:10.3389/fimmu.2017.00598
- Mullin G, et.al. Testing for Food Reactions: The Good, the Bad, and the Ugly. Nutr in Clin Pract. 2010; 25(2):192-198.
- Atkinson W, et. al. Food Elimination Based on IgG Antibodies in Irritable Bowel Syndrome: A Randomized Controlled Trial. Gut. 2004;53:1459-1464.
- Coucke F. Food intolerance in patients with manifest autoimmunity. Observational study. Autoimmune Rev. 2018 Nov;17(11):1078-1080.
- Wambre E, Jeong D. Oral Tolerance Development and Maintenance. Immunol Allergy Clin North Am. 2018;38(1):27-37. doi:10.1016/j.iac.2017.09.003
- Caminero, A., McCarville, J.L., Galipeau, H.J. et al. Duodenal bacterial proteolytic activity determines sensitivity to dietary antigen through protease-activated receptor-2. Nat Commun 10, 1198 (2019). https://doi.org/10.1038/s41467-019-09037-9
* IgG Food Explorer™ testing is not intended for disease diagnosis. Information provided by Diagnostic Solutions Laboratory does not constitute medical advice; but is for educational purposes only. Services provided are for laboratory testing only. No charge is incurred for ordering collection kits.