CytoDx
Cytokine Response Profile
CytoDX® from Diagnostic Solutions Laboratory is a cytokine response profile that evaluates serum cytokines to provide insight into systemic immune status.
Results from CytoDX offer practitioners insight into disease status, how well treatment is working, and into exacerbation or remission of illness so that they can better target treatment plants.
Documents
Explore our CytoDx Sample Report, Product Brief, and other educational resources. Learn about the markers on the test and how they impact overall health so you can better interpret results.
Clinical Information
Alterations in the immune system that result in chronic inflammation and autoimmunity have been linked to a wide range of health conditions and diseases. Cytokines are important mediators of many immune responses, and imbalances in cytokines have been shown to play key roles on chronic inflammation and autoimmunity.
Cytokines are key players in inflammation and immune system regulation. Elevated or diminished levels of specific cytokines can help diagnose various autoimmune and inflammatory diseases, such as rheumatoid arthritis, lupus, or inflammatory bowel disease.
Most cytokines can be generally characterized as pro-inflammatory or anti-inflammatory, depending on their primary effects on immune responses. Immune responses are often further characterized by the type of T helper (Th) cell involved.
CytoDx Panel Enables Practitioners to Assess Systemic Immune Status:
- Pro-inflammatory / anti-inflammatory cytokine balance
- Th1, Th2, Th17 and T-regulatory cytokine responses
- Efficacy of immune balancing and modulating approaches
CytoDx Analytes
| Pro-Inflammatory | Anti-Inflammatory |
|---|---|
| • GM-CSF • IFN gamma : Th1 • IL-1 beta • IL-2 : Th1 • IL-6 • IL-7 • IL-8 • IL-12 p70 : Th1 • IL-17A : Th17 • IL-18 • TNF alpha • IL-15 • MIP-1 beta (CCL4) • RANTES |
• IL-4 : Th2 • IL-5 : Th2 • IL-10 : Treg • IL-13 : Th2 |
Gut-Immune Connection
It is now widely recognized that GI health — particularly the health of the microbiome — plays a critical role in regulating immune function and has been shown to influence circulating cytokines such as IL-6, TNF-alpha, and IL-17. It is recommended to pair CytoDx with a GI-MAP™ stool test for best clinical assessment and to provide actionable direction.
Services provided are for laboratory testing only. No charge is incurred for ordering collection kits.